• Product NameABCB7 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total ABCB7 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human ABCB7.
• Target NameABCB7
• Alternative Names    ABC transporter 7 protein; ABC7; Anemia; sideroblastic; with spinocerebellar ataxia
• Accession No. Swiss-Prot: O75027
  NCBI Gene ID: 22
• UniprotO75027
• Gene ID22;
• SDS-PAGE MW 83kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  

Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.

Bekri S., Blood 96:3256-3264(2000).
Ross M.T., Nature 434:325-337(2005).
Maguire A., Br. J. Haematol. 115:910-917(2001).

• Western blot analysis of extracts from HepG2 cells, using ABCB7 antibody #34460.
• Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue using ABCB7 antibody #34460.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting