• Product NamePDE4C Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total PDE4C protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human PDE4C.
• Target NamePDE4C
• Alternative Names    cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; CN4C; DPDE1; PDE21
• Accession No. Swiss-Prot: Q08493
  NCBI Gene ID: 5143
• UniprotQ08493
• Gene ID5143;
• SDS-PAGE MW 80kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Engels P., FEBS Lett. 358:305-310(1995).
Sullivan M., Cell. Signal. 11:735-742(1999).
Ota T., Nat. Genet. 36:40-45(2004).

• Western blot analysis of extracts from A549 cells, RAW264.7 cells and HuvEc cells, using PDE4C antibody #34525.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting