• Product NameCLIP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total CLIP1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human CLIP1.
• Target NameCLIP1
• Alternative Names    CLIP-170; CLIP1; Cytoplasmic linker protein-170 alpha-2; Reed- Sternberg intermediate filament associated protein; REST
• Accession No. Swiss-Prot: P30622
  NCBI Gene ID: 6249
• UniprotP30622
• Gene ID6249;
• SDS-PAGE MW 161kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking.

Bilbe G., EMBO J. 11:2103-2113(1992).
Pierre P., Cell 70:887-900(1992). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).

• Western blot analysis of extracts from MCF-7 cells, RAW264.7 cells, HepG2 cells, COLO cells and HUVEC cells, using CLIP1 antibody #34529.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting