• Product NameCPM Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CPM protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human CPM.
• Target NameCPM
• Alternative Names    Carboxypeptidase M; EC 3.4.17.12; CPM;
• Accession No. Swiss-Prot: P14384
  NCBI Gene ID: 1368
• UniprotP14384
• Gene ID1368;
• SDS-PAGE MW 51kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

Tan F., J. Biol. Chem. 264:13165-13170(1989).
Skidgel R.A., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Bektas A., Diabetes 50:204-208(2001).

• Western blot analysis of extracts from A549 cells, using CPM antibody #34549.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting