• Product NameBORG4 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total BORG4 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human BORG4.
• Target NameBORG4
• Alternative Names    binder of Rho GTPases 4; BORG4; CDC42 effector protein (Rho GTPase binding) 4; Cdc42 effector protein 4; CEP4
• Accession No. Swiss-Prot: Q9H3Q1
  NCBI Gene ID: 23580
• UniprotQ9H3Q1
• Gene ID23580;
• SDS-PAGE MW 36kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation, when overexpressed in fibroblasts.

Osada N., J. Hum. Genet. 45:374-377(2000).
Hirsch D.S., J. Biol. Chem. 276:875-883(2001).
Olsen J.V., Cell 127:635-648(2006).

• Western blot analysis of extracts from Jurkat cells, using BORG4 antibody #34558.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting