• Product NameCEP152 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total CEP152 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human CEP152.
• Target NameCEP152
• Alternative Names    centrosomal protein 152 kDa; centrosomal protein 152kDa; centrosomal protein of 152 kDa;
• Accession No. Swiss-Prot: O94986
  NCBI Gene ID: 22995
• UniprotO94986
• Gene ID22995;
• SDS-PAGE MW 140kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles.

Nagase T., DNA Res. 5:355-364(1998).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Andersen J.S., Nature 426:570-574(2003).

• Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using CEP152 antibody #34565.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting