• Product NameKIF4A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total KIF4A protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human KIF4A.
• Target NameKIF4A
• Alternative Names    chromokinesin; chromosome-associated kinesin KIF4A; KIF4; KIF4-G1; kinesin family member 4
• Accession No. Swiss-Prot: O95239
  NCBI Gene ID: 24137
• UniprotO95239
• Gene ID24137;
• SDS-PAGE MW 140kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Motor protein that translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis. May play a role in mitotic chromosomal positioning and bipolar spindle stabilization.

Villard L., Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Oh S.J., Biochim. Biophys. Acta 1493:219-224(2000).
Rentsch A., Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.

• Western blot analysis of extracts from HeLa cells, using KIF4A antibody #34591.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting