• Product NameAPPL1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total APPL1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human APPL1.
• Target NameAPPL1
• Alternative Names    Adaptor protein APPL; Adaptor protein containing pH domain; PTB domain and leucine zipper motif; DIP13 alpha; DP13A
• Accession No. Swiss-Prot: Q9UKG1
  NCBI Gene ID: 26060
• UniprotQ9UKG1
• Gene ID26060;
• SDS-PAGE MW 80kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Required for the regulation of cell proliferation in response to extracellular signals from an early endosomal compartment. Links Rab5 to nuclear signal transduction.

Chen Y.Q., J. Biol. Chem. 277:26281-26285(2002).
Elledge S.J., Science 316:1160-1166(2007).
Mohammed S., Anal. Chem. 81:4493-4501(2009)

• Western blot analysis of extracts from A549 cells, using APPL1 antibody #34641.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting