• Product NameGGH Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total GGH protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human GGH.
• Target NameGGH
• Alternative Names    conjugase; EC 3.4.19.9; folylpolygammaglutamyl hydrolase; gamma-Glu-X carboxypeptidase; gamma-glutamyl hydrolase
• Accession No. Swiss-Prot: Q92820
  NCBI Gene ID: 8836
• UniprotQ92820
• Gene ID8836;
• SDS-PAGE MW 36kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.

Yao R., Proc. Natl. Acad. Sci. U.S.A. 93:10134-10138(1996).
Yin D., Gene 238:463-470(1999).
Basrur V., J. Proteome Res. 2:69-79(2003).

• Western blot analysis of extracts from RAW264.7 cells, using GGH antibody #34695.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting