• Product NameGLRB Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total GLRB protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human GLRB.
• Target NameGLRB
• Alternative Names    Glycine receptor subunit beta; Glycine receptor 58 kDa subunit;
• Accession No. Swiss-Prot: P48167
  NCBI Gene ID: 2743
• UniprotP48167
• Gene ID2743;
• SDS-PAGE MW 56kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing).

Handford C.A., Brain Res. Mol. Brain Res. 35:211-219(1996).
Milani N., Genomics 50:341-345(1998).
Ota T., Nat. Genet. 36:40-45(2004).

• Western blot analysis of extracts from A549 cells and K562 cells, using GLRB antibody #34705.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting