• Product NameMRC1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC IF/ICC ELISA
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total MRC1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human MRC1.
• Target NameMRC1
• Alternative Names    Macrophage mannose receptor 1; MMR; CD206 antigen;
• Accession No. Swiss-Prot: P22897
  NCBI Gene ID: 4360
• UniprotP22897
• Gene ID4360;
• SDS-PAGE MW 166kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000

  IHC 1:50-1:100

  IF/ICC 1:100-1:500

  ELISA(peptide) 1:20000-1:40000

Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.

Taylor M.E., J. Biol. Chem. 265:12156-12162(1990).
Ezekowitz R.A., J. Exp. Med. 172:1785-1794(1990).
Kim S.J., Genomics 14:721-727(1992).

• Western blot analysis of extracts from K562 cells, A549 cells and NIH-3T3 cells, using MRC1 antibody #34773.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting