• Product NameMINPP1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total MINPP1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human MINPP1.
• Target NameMINPP1
• Alternative Names    EC 3.1.3.62; inositol (1; 3; 4; 5)-tetrakisphosphate 3-phosphatase
• Accession No. Swiss-Prot: Q9UNW1
  NCBI Gene ID: 9562
• UniprotQ9UNW1
• Gene ID9562;
• SDS-PAGE MW 60kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification).

Caffrey J.J., FEBS Lett. 442:99-104(1999).
Chi H., Genomics 56:324-336(1999).
Wiemann S., Genome Res. 11:422-435(2001).

• Western blot analysis of extracts from 293 cells, using MINPP1 antibody #34811.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting