• Product NamePNPLA6 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total PNPLA6 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human PNPLA6.
• Target NamePNPLA6
• Alternative Names    Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6;
• Accession No. Swiss-Prot: Q8IY17
  NCBI Gene ID: 10908
• UniprotQ8IY17
• Gene ID10908;
• SDS-PAGE MW 150kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.

Lucas S.M., Nature 428:529-535(2004).
Venter J.C., Submitted (SEP-2005).
Korner R., Anal. Chem. 80:9526-9533(2008).

• Western blot analysis of extracts from COLO205 cells, using PNPLA6 antibody #34862.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting