• Product NameRGS12 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total RGS12 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from N-terminal of human RGS12.
• Target NameRGS12
• Alternative Names    regulator of G-protein signaling 12;
• Accession No. Swiss-Prot: O14924
  NCBI Gene ID: 6002
• UniprotO14924
• Gene ID6002;
• SDS-PAGE MW 156kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. soform 5:Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis.

Chatterjee T.K., J. Biol. Chem. 275:29660-29671(2000).
Snow B.E., J. Biol. Chem. 273:17749-17755(1998).
Hillier L.W., Nature 434:724-731(2005).

• Western blot analysis of extracts from 3T3 cells, using RGS12 antibody #34981.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting