Home
Antibodies
Covid-19 Test Kits
Diagnostic Kits
Proteins
ELISA Kits
About Us

STAT3(Phospho-Tyr705) Antibody #11045

Review:
Datasheet PDF
add to favorites
Catalog No. Package Size Price Quantity
50ul $189.00
100ul $279.00
Availability:Yes
Total:$789.00
ADD TO CART
 
Datasheet Images Protocol
Description
  • Product NameSTAT3(Phospho-Tyr705) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC IF
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of STAT3 only when phosphorylated at tyrosine 705.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 705 (A-P-Y(p)-L-K) derived from Human STAT3.
  • Target NameSTAT3
  • ModificationPhospho
  • ModificationPhospho
  • Alternative Names    APRF; Acute-phase response factor; HIES
  • Accession No. Swiss-Prot: P40763
    NCBI Protein: NP_003141.2
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Knockdown of CTCF reduces the binding of EZH2 and affects the methylation of the SOCS3 promoter in hepatocellular carcinoma.In Int J Biochem Cell Biol on 2020 Mar; by Wei L, Liu Q, et al..PMID: 31917284, , (2020),
PMID: 31917284 Effect of STAT3 decoy oligodeoxynucleotides mediated by ultrasound-targeted microbubbles combIned with ultrasound on the growth of squamous cell carcInoma of the esophagus. In Oncol Lett on 2019 Feb by Zhang Y, Zhang M, et al..PMID:30675281, , (2019),
PMID: 30675281 A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
PMID: 31594861 Detection of promoter methylation status of suppressor of cytokine signaling 3 (SOCS3) in tissue and plasma from Chinese patients with different hepatic diseases.In Clin Exp Med. On 2018 Feb by Wei L, Huang Y et al..PMID:28951980, , (2018),
PMID: 28951980 A novel IFIH1 mutation in the pincer domain underlies the clinical features of both Aicardi-Gouti res and Singleton-Merten syndromes in a single patient.In Br J Dermatol. On 2018 Feb by Takeichi T, Katayama C et al..PMID:29270977, , (2018),
PMID: 29270977 Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.In J Exp Clin Cancer Res. On 2018 Nov 27 by Qiang Z, Zhou ZY et al..PMID: 30482227, , (2018),
PMID: 30482227 Feng-Ze Wang, Peng-Jiao, Na-Na Yang PF-04691502 triggers cell cycle arrest, apoptosis and inhibits the angiogenesis in hepatocellular carcinoma cells, Toxicology Letters, 220:150¨C 156 (2013),
PMID: 23639247 Libing Ma, Jinxiu Li, Guyi Wang Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K¨CAkt signaling pathways., Regulatory Peptides., 181:9¨C16 (2013),
PMID: 23327998 Emilio Garc¨ªa-Prieto, Adri¨¢n Gonz¨¢lez-L¨®pez, Sandra Cabrera Resistance to Bleomycin-Induced Lung Fibrosis in MMP-8 Deficient Mice Is Mediated by Interleukin-10. , PLoS ONE, 5(10): e13242 (2010),
PMID: 20949050 Jian-Guo Zhang, Jing Zhao, Yan Xin Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions., World J Gastroenterol, 16(5): 571¨C577. (2010),
PMID: 20128024 Takuya Takeichi, Kazumitsu Sugiura, Yoshinao Muro Overexpression of LEDGF/DFS70 Induces IL-6 via p38 Activation in HaCaT Cells, Similar to that Seen in the Psoriatic Condition., Journal of Investigative Dermatology, 130(12):2760-2767 (2010),
PMID: 20631726 H Yamaguchi, J Zhu, T Yu Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation., Toxicology, 226:131-142 (2006),
PMID: 16860915 Please let us know if you have published research using #11045 so that we can cite your reference.

Customer Reviews and Rankings

No comment
Total 0 results, divided into1 pages. First Prev Next Last

My Review

Username:Anonymous user
E-mail:
Ratings:
Content:
Verification code:captcha

Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep