• Product NameSCN4B Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu Ms Rt
• SpecificityThe antibody detects endogenous levels of total SCN4B protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SCN4B.
• Target NameSCN4B
• Alternative Names    Sodium channel subunit beta-4 [Precursor]; SCN4B;
• Accession No. Swiss-Prot: P16949
  NCBI Gene ID: 6330
• UniprotP16949
• Gene ID3925;
• SDS-PAGE MW 27kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear By similarity.

Yu F.H., J. Neurosci. 23:7577-7585(2003).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Medeiros-Domingo A., Circulation 116:134-142(2007).

• Western blot analysis of extracts from HepG2 cells and Jurkat cells, using SCN4B antibody #35053.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting