• Product NameSLCO1B1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SLCO1B1 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SLCO1B1.
• Target NameSLCO1B1
• Alternative Names    Solute carrier family 21 member 6; Sodium-independent organic anion-transporting polypeptide 2; OATP 2; Liver-specific organic anion transporter 1; LST-1
• Accession No. Swiss-Prot: Q9Y6L6
  NCBI Gene ID: 10599
• UniprotQ9Y6L6
• Gene ID10599;
• SDS-PAGE MW 76kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Mediates the Na+-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver.

Kirchgessner T.G., J. Biol. Chem. 274:37161-37168(1999).
Keppler D., J. Biol. Chem. 275:23161-23168(2000).
Venter J.C., Submitted (JUL-2005).

• Western blot analysis of extracts from COLO205 and Jurkat cells, using SLCO1B1 antibody #35068.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting