• Product NameSFRS8 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SFRS8 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SFRS8.
• Target NameSFRS8
• Alternative Names    Splicing factor; arginine/serine-rich 8; Suppressor of white apricot protein homolog; SFRS8; SWAP
• Accession No. Swiss-Prot: Q12872
  NCBI Gene ID: 6433
• UniprotQ12872
• Gene ID6433;
• SDS-PAGE MW 105kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.

Denhez F., J. Biol. Chem. 269:16170-16179(1994).
Scherer S.E., Nature 440:346-351(2006).

• Western blot analysis of extracts from 293 cells, using SFRS8 antibody #35077.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting