• Product NameUSP11 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total USP11 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human USP11.
• Target NameUSP11
• Alternative Names    Deubiquitinating enzyme 11; Ubiquitin carboxyl-terminal hydrolase 11; ubiquitin carboxyl-terminal hydrolase; X-linked; ubiquitin specific peptidase 11
• Accession No. Swiss-Prot: P51784
  NCBI Gene ID: 8237
• UniprotP51784
• Gene ID8237;
• SDS-PAGE MW 105kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks.

Ross M.T., Nature 434:325-337(2005).
Ideguchi H., Biochem. J. 367:87-95(2002).
Swanson D.A., Hum. Mol. Genet. 5:533-538(1996).

• Western blot analysis of extracts from 293 cells, using USP11 antibody #35115.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting