• Product NameUSP36 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total USP36 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human USP36.
• Target NameUSP36
• Alternative Names    Ubiquitin carboxyl-terminal hydrolase 36; EC 3.1.2.15; Ubiquitin thioesterase 36; Ubiquitin-specific-processing protease 36; Deubiquitinating enzyme 36
• Accession No. Swiss-Prot: Q9P275
  NCBI Gene ID: 57602
• UniprotQ9P275
• Gene ID57602;
• SDS-PAGE MW 125kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• 
  Immunohistochemistry: 1:50~1:100
  

May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4) By similarity.

Nagase T., DNA Res. 7:143-150(2000).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).

• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using USP36 antibody #35121.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting