• Product NameTACC3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB IHC IF
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total TACC3 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human TACC3.
• Target NameTACC3
• Alternative Names    ERIC-1; ERIC1; TAC3; Transforming acidic coiled-coil-containing protein 3;
• Accession No. Swiss-Prot: Q9Y6A5
  NCBI Gene ID: 10460
• UniprotQ9Y6A5
• Gene ID10460;
• SDS-PAGE MW 80kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  Immunohistochemistry: 1:50~1:100
  Immunofluorescence: 1:100~1:500

Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors By similarity. May be involved in the control of cell growth and differentiation. May contribute to cancer.

Still I.H., Genomics 58:165-170(1999).
McKeveney P.J. Br. J. Haematol. 112:1016-1024(2001).
Gangisetty O., Oncogene 23:2559-2563(2004).

• Western blot analysis of extracts from 293 cells and HUVEC cells, using TACC3 antibody #35171.
• Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using TACC3 antibody #35171.
• Immunofluorescence analysis of A549cells, using TACC3 antibody #35171.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting