Home
Antibodies
Proteins
IVD Raw Materials
Assay Kits
ELISA Kits
KD/KO Validation
About Us
Enzymes

PKM2 Antibody #21578

Review:
Datasheet PDF
add to favorites
Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
Total:
ADD TO CART
 
Datasheet Images Protocol
Description
  • Product NamePKM2 Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • ApplicationsWB IF
  • Species ReactivityHu
  • SpecificityThe antibody detects endogenous levels of total PKM2 protein.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around aa.405~409(T-S-D-P-T) derived from Human PKM2.
  • Target NamePKM2
  • Alternative Names    PKM; PK3; OIP3; PK2;
  • Accession No. Swiss-Prot: P14618-1
    NCBI Protein: NP_872270.1
  • UniprotP14618
  • Gene ID5315;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

Single-Cell FISH Analysis Reveals Distinct Shifts in PKM Isoform Populations during Drug Resistance Acquisition. In Biomolecules on 2022 Aug 6 by Seong Ho Kim, Ji Hun Wi, et al..PMID:36008976, , (2022),
PMID: 36008976
PK-M2-mediated metabolic changes In breast cancer cells Induced by ionizIng radiation. In Breast Cancer Res Treat on 2019 Nov by Zhang L, Bailleul J, et al..PMID: 31372790 , , (2019),
PMID: 31372790
IGF-1-mediated PKM2/β-catenin/miR-152 Regulatory Circuit in Breast Cancer.In Sci Rep on 2017 Nov 21 by Yi-Yang Wen, Wei-Tao Liu,et al..PMID: 29162853, , (2017),
PMID: 29162853
Nuclear PKM2 expression, an independent risk factor for ER after curative resection of hepatocellular carcinoma.In Biomed Pharmacother.On 2016 Dec by Fan F, Wu H et al..PMID: 27894667 , , (2016),
PMID: 27894667
View All Published Papers EGFR phosphorylates FAM129B to promote Ras activation.In Proc Natl Acad Sci USA on 2016 Jan 19 by Haitao Ji, Jong-Ho Lee et al..PMID:26721396, , (2016),
PMID: 26721396
PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis.In Nat Commun on 2016 Aug 3 by Ji Liang , Ruixiu Cao et al..PMID: 27485204, , (2016),
PMID: 27485204
Relationship between 18-F-fluoro-deoxy-d-glucose uptake and expression of glucose transporter 1 and pyruvate kinase M2 in intrahepatic cholangiocarcinoma.In Dig Liver Dis on 2015 Jul by et al..PMID: 25912843, , (2015),
PMID: 25912843
PKM2 regulates chromosome segregation and mitosis progression of tumor cells.In Mol Cell on 2014 Jan 9 by Yuhui Jiang, Xinjian Li et al..PMID: 24316223, , (2014),
PMID: 24316223
PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.In Nat Commun on 2014 Nov 21 by Yuhui Jiang , Yugang Wang et al..PMID: 25412762, , (2014),
PMID: 25412762
Insulin regulates glucose consumption and lactate production through reactive oxygen species and pyruvate kinase M2. In Oxid Med Cell Longev on 2014 by Qi Li, Xue Liu, et al..PMID:24895527, , (2014),
PMID: 24895527
Nuclear PKM2 Regulates the Warburg Effect.In Cell Cycle on 2013 Oct 1 by Weiwei Yang, Zhimin Lu,et al..PMID:24013426, , (2013),
PMID: 24013426
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect.In Nat Cell Biol on 2012 Dec by Weiwei Yang, Yanhua Zheng,et al..PMID:23178880, , (2012),
PMID: 23178880
PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis. In Cell on 2012 Aug 17 by Weiwei Yang, Yan Xia, et al..PMID: 22901803, , (2012),
PMID: 22901803
Please let us know if you have published research using #21578 so that we can cite your reference.

Customer Reviews and Rankings

No comment
Total 0 results, divided into1 pages. First Prev Next Last

My Review

Username:Anonymous user
E-mail:
Ratings:
Content:
Verification code:captcha

Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep