• Product NameCytochrome P450 11B1/2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total Cytochrome P450 11B1/2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human Cytochrome P450 11B1/2.
• Target NameCytochrome P450 11B1/2
• Alternative Names    C11B1; CPN1; CYP11B; CYP11B1; CYPXIB1
• Accession No. Swiss-Prot: P15538/P19099
  NCBI Gene ID: 1584/1585
• UniprotP15538
• Gene ID1584;
• SDS-PAGE MW 58kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.

Mornet E., J. Biol. Chem. 264:20961-20967(1989).
Kawamoto T., FEBS Lett. 269:345-349(1990).
Nusbaum C., Nature 439:331-335(2006).

• Western blot analysis of extracts from COLO205 cells, using Cytochrome P450 11B1/2 antibody #35212.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting