• Product NameIL15RA Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total IL15RA protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human IL15RA.
• Target NameIL15RA
• Alternative Names    Interleukin-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; IL15RA;
• Accession No. Swiss-Prot: Q13261
  NCBI Gene ID: 3601
• UniprotQ13261
• Gene ID3601;
• SDS-PAGE MW 32kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK.

Anderson D.M., J. Biol. Chem. 270:29862-29869(1995).
Yu W., Genome Res. 7:353-358(1997).
Ebert L., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

• Western blot analysis of extracts from COLO cells, using IL15RA antibody #35222.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting