• Product NameSNIP Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total SNIP protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human SNIP.
• Target NameSNIP
• Alternative Names    p130Cas-associated protein; P140; p140Cap; SNAP-25-interacting protein;
• Accession No. Swiss-Prot: Q9C0H9
  NCBI Gene ID: 80725
• UniprotQ9C0H9
• Gene ID80725;
• SDS-PAGE MW 112kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.

Oka M., Submitted (DEC-2003).
Sugano S., Nat. Genet. 36:40-45(2004).
Ohara O., DNA Res. 7:347-355(2000).

• Western blot analysis of extracts from HepG2 and HeLa cells, using SNIP antibody #35235.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting