• Product NameCytochrome P450 4A11/22 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CYTOCHROME P450 4A11/22 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human CYTOCHROME P450 4A11/22.
• Target NameCytochrome P450 4A11/22
• Alternative Names    CYP4A11 protein;
• Accession No. Swiss-Prot: Q02928/Q5TCH4
  NCBI Gene ID: 1579/284541
• UniprotQ02928
• Gene ID1579;
• SDS-PAGE MW 60kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).

Capdevila J.H., Arch. Biochem. Biophys. 409:221-227(2003).
Bentley D.R., Nature 441:315-321(2006).
Shin H.D., J. Hum. Genet. 50:259-263(2005).

• Western blot analysis of extracts from COLO205, HuvEc and HeLa cells, using CYTOCHROME P450 4A11/22 antibody #35260.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting