• Product NameCYP39A1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total CYP39A1protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human CYP39A1.
• Target NameCYP39A1
• Alternative Names    24-hydroxycholesterol 7-alpha-hydroxylase; CP39A; CYP39A1; Cytochrome P450 39A1; cytochrome P450
• Accession No. Swiss-Prot: Q9NYL5
  NCBI Gene ID: 51302
• UniprotQ9NYL5
• Gene ID51302;
• SDS-PAGE MW 54kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product.

Li-Hawkins J., J. Biol. Chem. 275:16543-16549(2000).
Ota T., Nat. Genet. 36:40-45(2004).
Mungall A.J., Nature 425:805-811(2003).

• Western blot analysis of extracts from 293/HeLa cells, using CYP39A1 antibody #35272.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting