• Product NameIRAK2 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total IRAK2 protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from Internal of human IRAK2.
• Target NameIRAK2
• Alternative Names    interleukin-1 receptor associated kinase-2; interleukin-1 receptor-associated kinase 2; Interleukin-1 receptor-associated kinase-like 2; IRAK-2; IRAK2
• Accession No. Swiss-Prot: O43187
  NCBI Gene ID: 3656
• UniprotO43187
• Gene ID3656;
• SDS-PAGE MW 70kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Rosati O., Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Muzio M., Science 278:1612-1615(1997).
Wesche H., J. Biol. Chem. 274:19403-19410(1999).

• Western blot analysis of extracts from 293 cells, using IRAK2 antibody #35287.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting