• Product NameFCGR2A Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total FCGR2A protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from C-terminal of human FCGR2A.
• Target NameFCGR2A
• Alternative Names    Low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a
• Accession No. Swiss-Prot: P12318
  NCBI Gene ID: 2212
• UniprotP12318
• Gene ID2212;
• SDS-PAGE MW 35kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.

Stuart S.G., J. Exp. Med. 166:1668-1684(1987).
Brooks D.G., J. Exp. Med. 170:1369-1385(1989).
Gregory S.G., Nature 441:315-321(2006).

• Western blot analysis of extracts from HeLa cells, using FCGR2A antibody #35305.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting