• Product NameTNFRSF10D Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• ApplicationsWB
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total TNFRSF10D protein.
• Immunogen TypePeptide
• Immunogen DescriptionSynthesized peptide derived from internal of human TNFRSF10D.
• Target NameTNFRSF10D
• Alternative Names    Tumor necrosis factor receptor superfamily member 10D; Decoy receptor 2; DcR2; TNF-related apoptosis-inducing ligand receptor 4; TRAIL receptor 4
• Accession No. Swiss-Prot: Q9UBN6
  NCBI Gene ID: 8793
• UniprotQ9UBN6
• Gene ID8793;
• SDS-PAGE MW 42kd
• Concentration 1.0mg/ml
• Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Storage Store at -20˚C

• Western blotting: 1:500~1:3000
  
  

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to it cannot but according to it can induce the NF-kappa-B pathway.

Marsters S.A., Curr. Biol. 7:1003-1006(1997).
Degli-Esposti M.A., Immunity 7:813-820(1997).
Pan G., FEBS Lett. 424:41-45(1998).

• Western blot analysis of extracts from Jurkat cells, using TNFRSF10D antibody #35312.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting