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STAT5a(Phospho-Tyr694) Antibody #11048

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Catalog No. Package Size Price Quantity
50ul $219.00
100ul $319.00
Availability:Yes
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Description
  • Product NameSTAT5a(Phospho-Tyr694) Antibody
  • Host SpeciesRabbit
  • ClonalityPolyclonal
  • PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • ApplicationsWB IHC
  • Species ReactivityHu Ms Rt
  • SpecificityThe antibody detects endogenous level of STAT5A only when phosphorylated at tyrosine 694.
  • Immunogen TypePeptide-KLH
  • Immunogen DescriptionPeptide sequence around phosphorylation site of tyrosine 694 (D-G-Y(p)-V-K) derived from Human STAT5A.
  • Target NameSTAT5a
  • ModificationPhospho
  • Alternative Names    MGF; MPF; Mammary gland factor; STA5A,; STAT5
  • Accession No. Swiss-Prot: P42229
    NCBI Protein: NP_003143.2
  • UniprotP42229
  • Gene ID6776;
  • Concentration 1.0mg/ml
  • Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Application Details
Background

Published Papers

A thiazole-derived oridonIn analogue exhibits antitumor activity by directly and allosterically InhibitIng STAT3. In J Biol Chem on 2019 Nov 15;by Shen X, Zhao L,et al..PMID:31594861, , (2019),
PMID: 31594861
The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V.In Mol Oncol on 2014 May by Laura A No?l , Florence A Arts et al..PMID:24618081, , (2016),
PMID: 24618081
JAK3 deregulation by activating mutations confers invasive growth advantage in extranodal nasal-type natural killer cell lymphoma.In Leukemia on 2014 Feb by A Bouchekioua 1 , L Scourzic et al..PMID: 23689514, , (2014),
PMID: 23689514
PDGFRA alterations in cancer: characterization of a gain-of-function V536E transmembrane mutant as well as loss-of-function and passenger mutations.In Oncogene on 2014 May 15 by A I Velghe, S Van Cauwenberghe et al..PMID:23752188 , , (2014),
PMID: 23752188
View All Published Papers Characterization of the rat oncostatin M receptor complex which resembles the human, but differs from the murine cytokine receptor. In PLoS One on 2012 by Johannes Drechsler, Joachim Gr?tzinger, et al..PMID: 22937020, , (2012),
PMID: 22937020
Downregulation of CCND1 and CDK6 by miR-34a Induces Cell Cycle Arrest.In FEBS Lett on 2008 Apr 30 by Fang Sun, Hanjiang Fu,et al..PMID:18406353, , (2008),
PMID: 18406353
Please let us know if you have published research using #11048 so that we can cite your reference.

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Application

WBWestern Blotting

IHCImmunohistochemistry

IFImmunofluorescence

ICCImmunocytochemistry

FCFlow Cytometry

IPImmunoprecipitation

EELISA

DBDot Blotting

ChIPChromatin Immunoprecipitation

GICAGold Immunochromatography Assay

NCNegative Control

Species Reactivity

HuHuman

MsMouse 

RtRat 

Dm Drosophila melanogaster

C Caenorhabditis elegans

MkMonkey

RbRabbit

B Bovine 

D Dog

PPig

HmHamster

ChHm Chinese Hamster 

ChkChicken  

ShpSheep