• Product NameACVRL1 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntibodies were purified by antigen-affinity chromatography.
• ApplicationsWB
• Species ReactivityHu Ms
• SpecificityThe antibody detects endogenous levels of total ACVRL1 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionRecombinant fragment corresponding to a region within amino acids 109 and 311 of ACVRL1.
• Target NameACVRL1
• Alternative Names    ACVRLK1 antibody; ALK-1 antibody; ALK1 antibody; HHT antibody; HHT2 antibody; ORW2 antibody; SKR3 antibody; TSR-I antibody; ACVRL1 antibody; TGF-B superfamily receptor type I antibody; serine/threonine-protein kinase receptor R3 antibody; activin receptor
• Accession No. Swiss-Prot#:P37023;
  NCBI Gene#:94
• UniprotP37023
• Gene ID94;
• SDS-PAGE MW 56kd
• Concentration 0.78mg/ml
• Formulation Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Storage Store at -20˚C

• Western blotting: 1:500-1:3000
  

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]

• Sample(30 μg of whole cell lysate)
  A:Hep G2
  7.5% SDS PAGE
  #35383 diluted at 1:1000
• Sample (30 ug of whole cell lysate)
  
  A:NIH-3T3
  7.5% SDS PAGE
  
  #35383 diluted at 1:1000
  

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting