• Product NameTONSL Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total TONSL protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to residues near the C terminal of human tonsoku-like, DNA repair protein
• Target NameTONSL
• Alternative Names    IKBR; NFKBIL2
• Accession No. Swiss-Prot#: Q96HA7
  NCBI Gene ID: 4796
  Gene Accssion: BC008782
• UniprotQ96HA7
• Gene ID4796;
• Concentration 2.2mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:100-1:300

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.?

• Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using #35590 at dilution 1/60.
• Immunohistochemical analysis of paraffin-embedded Human brain cancer tissue using #35590 at dilution 1/60.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting