• Product NameDIRAS3 Antibody
• Host SpeciesRabbit
• ClonalityPolyclonal
• PurificationAntigen affinity purification.
• ApplicationsIHC
• Species ReactivityHu
• SpecificityThe antibody detects endogenous levels of total DIRAS3 protein.
• Immunogen TypeRecombinant Protein
• Immunogen DescriptionFusion protein corresponding to residues near the N terminal of human DIRAS family, GTP-binding RAS-like 3
• Target NameDIRAS3
• Alternative Names    ARHI; NOEY2
• Accession No. Swiss-Prot#: O95661
  NCBI Gene ID: 9077
  Gene Accssion: BC005362
• UniprotO95661
• Gene ID9077;
• Concentration 1mg/ml
• Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Storage Store at -20˚C

• Immunohistochemistry: 1:15-1:50

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

• Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using #36135 at dilution 1/25.
• Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using #36135 at dilution 1/25.

• Flow Cytometry (FCM) General Protocol
• Immunofluorescence(IC)
• Immunohistochemistry(Polymer)
• Western Blotting