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Location： Home > Phospho Antibodies > Ezrin(Phospho-Thr567) Antibody

Ezrin(Phospho-Thr567) Antibody#11202

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Product Detail

Product NameEzrin(Phospho-Thr567) Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityThe antibody detects endogenous level of Ezrin only when phosphorylated at threonine 567.

Immunogen TypePeptide-KLH

Immunogen DescPeptide sequence around phosphorylation site of threonine 567 (Y-K-T(p)-L-R) derived from Human Ezrin.

Target NameEzrin

ConjugateUnconjugated

Other NamesCytovillin; EZRI; VIL2; Villin 2; p81

Accession NoSwiss-Prot: P15311
NCBI Protein: NP_001104547.1

Uniprot P15311

Gene ID 7430;

Concentration1.0mg/ml

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

StorageStore at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Application Details

WB 1:500 - 1:2000

Western blot analysis of extracts from MDA cells untreated or treated with anisomycin using Ezrin(Phospho-Thr567) Antibody #11202.

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008],

If you have published an article using product 11202, please notify us so that we can cite your literature.

et al,Expression of Ezrin and Phosphorylated Ezrin (pEzrin) in Pancreatic Ductal Adenocarcinoma. , (2010),
PMID: 20158339
et al,Cosmc-dependent mucin-type O-linked glycosylation is essential for podocyte function.In Am J Physiol Renal Physiol on 2020 Feb by Stotter BR, Talbot BE, et al..PMID:31904283 , (2020),
PMID: 31904283
et al,Expression of Ezrin and Phosphorylated Ezrin (pEzrin) in Pancreatic Ductal Adenocarcinoma.In Cancer Invest on 2010 Mar by Cui Y1, Li T,et al..PMID:20158339 , (2010),
PMID: 20158339
et al,Prognostic implications of ezrin and phosphorylated ezrin expression in non-small cell lung cancer.In BMC Cancer on 2014 Mar 15 by Tiefeng Jin, Jingchun Jin et al ..PMID: 24629131 , (2014),
PMID: 24629131
et al,Clustered PI (4, 5) P2 accumulation and ezrin phosphorylation in response to CLIC5A. In J Cell Sci on 2014 Dec 15 by Abass Al-Momany, Laiji Li, et al..PMID:25344252 , (2014),
PMID: 25344252
et al,Clustered phosphatidylinositol 4, 5 bisphosphate accumulation and ezrin phosphorylation in response to CLIC5A. In J Cell Sci on 2014 Dec 15 by Abass Al-Momany, Laiji Li,et al..PMID:25344252 , (2014),
PMID: 25344252

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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