Product Detail
Product NameATG9B Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAffinity chromatography purified via peptide column
ApplicationsELISA WB ICC
Species ReactivityHu Ms Rt
Immunogen TypePeptide
Immunogen DescRaised against a 17 amino acid peptide near the carboxy terminus of human ATG9B.
Target NameATG9B
ConjugateUnconjugated
Other NamesAutophagy-related protein 9B, APG9L2, APG9-like 2, Nitric oxide synthase 3-overlapping antisense gene protein, NOS3AS
Accession NoSwiss-Prot:Q674R7
Gene ID:285973
Uniprot
Q674R7
Gene ID
285973;
Concentration1mg/ml
FormulationSupplied in PBS containing 0.02% sodium azide.
StorageCan be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Application Details
Western blot analysis of ATG9B in HeLa cell lysate with ATG9B antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry of ATG9B in HeLa cells with ATG9B antibody at 10 ug/mL.
Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it’s highly expressed in placenta and pituitary gland.
If you have published an article using product 25131, please notify us so that we can cite your literature.
et al,Depletion of CPNE7 sensitizes colorectal cancer to 5-fluorouracil by downregulating ATG9B expression. In J Cell Mol Med
on 2024 Apr by Weile Xu, Yujie Tang,et al..PMID:38526029
, (2024),
PMID:
38526029
Yes
