Product Detail
Product NameZBTB3 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAffinity chromatography purified via peptide column
ApplicationsELISA WB IHC
Species ReactivityHu Ms Rt
SpecificityAt least three isoforms of ZBTB3 are known to exist. This antibody is predicted to not cross-react with other ZBTB protein family members.
Immunogen TypePeptide
Immunogen DescRaised against a 17 amino acid peptide near the carboxy terminus of human ZBTB3.
Target NameZBTB3
ConjugateUnconjugated
Other NamesZinc finger and BTB domain-containing protein 3
Accession NoSwiss-Prot:Q9H5J0
Gene ID:
Uniprot
Q9H5J0
Gene ID
79842;
Concentration1mg/ml
FormulationSupplied in PBS containing 0.02% sodium azide.
StorageCan be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Application Details
Western blot analysis of ZBTB3 in rat brain tissue lysate with ZBTB3 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry of ZBTB3 in human brain tissue with ZBTB3 antibody at 2.5 ug/mL.
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB3, the related protein ZBTB2 is thought to be phosphorylated in response to the DNA damage, probably by either ATM or ATR. Other ZBTB proteins, such as ZBTB4 and ZBTB38 bind methylated DNA and repress transcription, suggesting that ZBTB3 may also act as a transcription repressor.
If you have published an article using product 25242, please notify us so that we can cite your literature.
et al,LncKdm2b controls self-renewal of embryonic stem cells via activating expression of transcription factor Zbtb3. In EMBO J. On 2018 Apr 13 by Ye B, Liu B et al..PMID: 29535137
, (2018),
PMID:
29535137
Yes
