Product Detail
Product NameULBP2 Polyclonal Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
Immunogen DescRecombinant fusion protein of human ULBP2 (NP_079493.1).
ConjugateUnconjugated
Other NamesULBP2; ALCAN-alpha; N2DL2; NKG2DL2; RAET1H; NKG2D ligand 2
Accession NoSwiss-Prot#:Q9BZM5
NCBI Gene ID:80328
Uniprot
Q9BZM5
Gene ID
80328;
Calculated MWRefer to figures
FormulationAvoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Immunofluorescence analysis of U2OS cells using ULBP2 at dilution of 1:100. Blue: DAPI for nuclear staining.
This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
If you have published an article using product 28866, please notify us so that we can cite your literature.
et al,Delivery of Biomimetic Liposomes via Meningeal Lymphatic Vessels Route for Targeted Therapy of Parkinson’s DiseaseIn Research (Wash D C)On 2023 Jan 30byJing Liu , Duyang Gao et al..PMID:37040500
, (2023),
PMID:
37040500
et al,Nano-System Delivery Through the Meningeal Lymphatic System for Brain Disease Therapeutic Research
, (2023),
PMID:
Yes
