Product Detail
Product NameCleaved-caspase 3 antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationImmunogen affinity purified
ApplicationsWB IHC
Species ReactivityHu Ms Rt
SpecificityCaspase 3 (p17,Cleaved-Asp175) Antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.
Target NameCleaved-caspase 3
ConjugateUnconjugated
Other NamesApopain precursor; CASP-3; CPP-32; CPP32; Caspase-3; Cysteine protease CPP32; ICE3; SCA-1; SREBP cleavage activity 1; Yama protein,p17
Accession NoSwiss-Prot#: P42574
Uniprot
P42574
Gene ID
836;
Sdspage MW17KD
Concentration1.0mg/ml
FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20°C/1 year
Application Details
WB: 1:500-1:2000
IHC: 1:50-1:200
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme.
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