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IkB-alpha Antibody#29054

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Product Detail

Product NameIkB-alpha Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationImmunogen affinity purified

ApplicationsWB

Species ReactivityHu Ms Rt

SpecificityIkappaB-alpha Antibody detects endogenous levels of total IkappaB-alpha

Immunogen TypePeptide

Immunogen DescA synthesized peptide derived from human IkappaB-alpha

Target NameIkB-alpha

ConjugateUnconjugated

Other NamesI-kappa-B-alpha, IKBA, IkappaB alpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappaB inhibitor alpha, NFKBI, NFKBIA, RL/IF-1

Accession NoSwiss-Prot#: P25963

Uniprot P25963

Gene ID 4792;

Sdspage MW39KD

Concentration1.0mg/ml

FormulationRabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20°C/1 year

Application Details

 WB: 1:500-1:2000

 NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm.

If you have published an article using product 29054, please notify us so that we can cite your literature.

et al,Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.In J Exp Clin Cancer Res. On 2018 Nov 27 by Qiang Z, Zhou ZY et al..PMID: 30482227 , (2018),
PMID: 30482227
et al,Indirect effect of PM1 on endothelial cells via InducIng the release of respiratory Inflammatory cytokInes. In Toxicol In Vitro on 2019 Jun by Tian G, Wang J, et al..PMID: 30858030 , (2019),
PMID: 30858030
et al,Costunolide improved dextran sulfate sodium-induced acute ulcerative colitis in mice through NF-kB, STAT1/3, and Akt signaling pathways. In Int Immunopharmacol on 2020 Jul by Fan Xie, Hai Zhang, et al..PMID:32413737 , (2020),
PMID: 32413737

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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