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SOD1 Antibody#32058

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Product Detail

Product NameSOD1 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC,IF

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody detects endogenous level of total SOD1 protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant fusion protein of human SOD1 (NP_000445.1).

Target NameSOD1

ConjugateUnconjugated

Other NamesSOD1;ALS;ALS1;HEL-S-44;IPOA;SOD;hSod1;homodimer

Accession NoUniprot:P00441
GeneID:6647

Uniprot P00441

Gene ID 6647

Sdspage MW16-18KDa

Concentration1.0mg/ml

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of various cell lines, using SOD1 antibody.
Immunohistochemistry of paraffin-embedded human liver using SOD1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat liver using SOD1 Rabbit pAb.
Immunofluorescence analysis of NIH/3T3 cells using SOD1 Rabbit pAb.
Immunofluorescence analysis of U2OS cells using SOD1 Rabbit pAb.
Immunohistochemistry of paraffin-embedded mouse kidney using SOD1 Rabbit pAb.
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

If you have published an article using product 32058, please notify us so that we can cite your literature.

et al,The effect of exposure time and concentration of airborne PM2.5 on lung Injury In mice: A transcriptome analysis. In Redox Biol on 2019 Sep by Wang H, Shen X et al..PMID:31279222 , (2019),
PMID: 31279222
et al,Alveolar Type II Cell Damage and Nrf2-SOD1 Pathway Downregulation Are Involved in PM2.5-Induced Lung Injury in Rats. In Int J Environ Res Public Health on 2022 Oct 8 by Rui Niu, Jie Cheng,et al..PMID:36232201 , (2022),
PMID: 36232201

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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