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SIRT7 Antibody#32106

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Product Detail

Product NameSIRT7 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IF

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody detects endogenous level of total SIRT7 protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant fusion protein of human SIRT7 (NP_057622.1).

Target NameSIRT7

ConjugateUnconjugated

Other NamesSIRT7;SIR2L7;sirtuin 7

Accession NoUniprot:Q9NRC8
GeneID:51547

Uniprot Q9NRC8

Gene ID 51547

Sdspage MW45KDa

Concentration1.0mg/ml

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Immunofluorescence analysis of U2OS cells using SIRT7 Rabbit pAb.
Western blot analysis of extracts of various cell lines, using SIRT7 antibody.
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

If you have published an article using product 32106, please notify us so that we can cite your literature.

et al,Phosphorylation of SIRT7 by ATM causes DNA mismatch repair downregulation and adaptive mutability during chemotherapy. , (2025),
PMID: 39908142

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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