Product Detail
Product NameHGF Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total HGF protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human HGF (NP_001010933.1).
Target NameHGF
ConjugateUnconjugated
Other NamesHGF;DFNB39;F-TCF;HGFB;HPTA;SF
Accession NoUniprot:P14210
GeneID:3082
Uniprot
P14210
Gene ID
3082
Sdspage MW54KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Western blot analysis of extracts of Rat liver, using HGF antibody.
Western blot analysis of extracts of various cell lines, using HGF antibody.
Immunohistochemistry of paraffin-embedded mouse spinal cord using HGF Rabbit pAb.
Immunofluorescence analysis of HepG2 cells using HGF Rabbit pAb.
Immunohistochemistry of paraffin-embedded rat kidney using HGF Rabbit pAb.
This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.
If you have published an article using product 32218, please notify us so that we can cite your literature.
et al,Human umbilical cord mesenchymal stem cell-derived extracellular vesicles enhance the regenerative capability of fibrotic liver
, (2023),
PMID:
Yes
