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TYR Antibody#32259

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Product Detail

Product NameTYR Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were purified by affinity purification using immunogen.

ApplicationsWB IHC

Species ReactivityHuman,Rat,Mouse

SpecificityThe antibody detects endogenous level of total TYR protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant protein of human TYR.

Target NameTYR

ConjugateUnconjugated

Other NamesCMM8; OCA1A; OCAIA; SHEP3;

Accession NoSwiss-Prot:P14679
NCBI Gene ID:7299

Uniprot P14679

Gene ID 7299;

Sdspage MW60KD

Concentration1.0mg/ml

FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

StorageStore at -20˚C

Application Details

Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100

Western blot analysis of HepG2 cell lysate using TYR antibody.
Immunohistochemical analysis of paraffin-embedded human stomach cancer using TYR antibody at dilution of 1:100 (200x lens).

The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

If you have published an article using product 32259, please notify us so that we can cite your literature.

et al,Discovery of a Novel Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2) and Cyclin-Dependent Kinase 4 (CDK4) Dual Inhibitor for the Treatment of Triple-Negative Breast Cancer , (2022),
PMID:

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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