Product Detail
Product NameG6PD Antibody
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationAffinity purification
ApplicationsWB,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total G6PD protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant fusion protein of human G6PD (NP_000393.4).
Target NameG6PD
ConjugateUnconjugated
Other NamesG6PD;G6PD1
Accession NoUniprot:P11413
GeneID:2539
Uniprot
P11413
Gene ID
2539
Sdspage MW60KDa
Concentration1.0mg/ml
FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.
StorageStore at -20˚C. Avoid freeze / thaw cycles.
Application Details
WB 1:500 - 1:2000
IF 1:50 - 1:200
Immunofluorescence analysis of HeLa cells using G6PD Rabbit pAb.
Western blot analysis of extracts of various cell lines, using G6PD antibody.
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
If you have published an article using product 32301, please notify us so that we can cite your literature.
et al,Activity of glucose-6-phosphate dehydrogenease and its correlation with inflammatory factors in diabetic retinopathy. In PLoS One
on 2024 Dec 2 by Dan Liu, Chuchu Cheng,et al..PMID:39621725
, (2024),
PMID:
39621725
Yes
