Product Detail
Product NameIFNAR2 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationAntibodies were purified by affinity purification using immunogen.
ApplicationsWB,IHC,IF
Species ReactivityHuman,Mouse,Rat
SpecificityThe antibody detects endogenous level of total IFNAR2 protein.
Immunogen TypeRecombinant Protein
Immunogen DescRecombinant protein of human IFNAR2.
Target NameIFNAR2
ConjugateUnconjugated
Other NamesIFN-R; IFNABR; IFNARB; IFN-alpha-REC;
Accession NoSwiss-Prot:P48551
NCBI Gene ID:3455
Uniprot
P48551
Gene ID
3455;
Sdspage MW58KD
Concentration1.0mg/ml
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Immunohistochemistry of paraffin-embedded human colon carcinoma using IFNAR2 at dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using IFNAR2 at 1:1000 dilution.
Immunofluorescence analysis of U2OS cells using IFNAR2 . Blue: DAPI for nuclear staining.
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
If you have published an article using product 32426, please notify us so that we can cite your literature.
et al,Inhibition of TPL2 by interferon-α suppresses bladder cancer through activation of PDE4D.In J Exp Clin Cancer Res. On 2018 Nov 27 by Qiang Z, Zhou ZY et al..PMID: 30482227
, (2018),
PMID:
30482227
Yes
