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MERTK Antibody#32851

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Product Detail

Product NameMERTK Antibody

Host SpeciesRabbit

ClonalityPolyclonal

IsotypeIgG

PurificationAffinity purification

ApplicationsWB,IHC

Species ReactivityHuman,Mouse,Rat

SpecificityThe antibody detects endogenous level of total MERTK protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant fusion protein of human MERTK (NP_006334.2).

Target NameMERTK

ConjugateUnconjugated

Other NamesMERTK;MER;RP38;Tyro12;c-Eyk;c-mer

Accession NoUniprot:Q12866
GeneID:10461

Uniprot Q12866

Gene ID 10461

Sdspage MW150-200KDa

Concentration1.0mg/ml

FormulationPBS with 0.02% sodium azide,50% glycerol,pH7.3.

StorageStore at -20˚C. Avoid freeze / thaw cycles.

Application Details
WB 1:500 - 1:2000
IHC 1:50 - 1:200
Western blot analysis of extracts of HepG2 cells, using MERTK antibody.
Western blot analysis of extracts of Mouse spleen, using MERTK antibody.
Immunohistochemistry of paraffin-embedded rat spleen using MERTK Rabbit pAb.
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

If you have published an article using product 32851, please notify us so that we can cite your literature.

et al,Disruption of MerTK increases the efficacy of checkpoint inhibitor by enhancing ferroptosis and immune response in hepatocellular carcinoma. In Cell Rep Med on 2024 Feb 20 by Shun Wang, Le Zhu,et al..PMID:38382467 , (2024),
PMID: 38382467

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
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