Product Detail
Product NameMART-1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsWB IHC
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total MART-1 protein.
Immunogen TypePeptide
Immunogen DescSynthesized peptide derived from human MART-1.
Target NameMART-1
ConjugateUnconjugated
Other NamesMART-1; MART1; melan-A; MELAN A; MELANOMA ANTIGEN RECOGNIZED BY T CELLS 1
Accession NoSwiss-Prot: Q16655
NCBI Gene ID: 2315
Uniprot
Q16655
Gene ID
2315;
Sdspage MW15kd
Concentration1.0mg/ml
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Western blot analysis of extracts from NIH/3T3 cells, using MART-1 antibody #33429.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MART-1 antibody #33429.
Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Toshihiko Hoashi, J. Biol. Chem., Apr 2005; 280: 14006 - 14016.
Maria P. Bettinotti, J. Immunol., Jul 1998; 161: 877.
P. J. Frost, J. Immunol., Mar 2001; 166: 3564.
Flora Wang, Clin. Cancer Res., Oct 1999; 5: 2756.
If you have published an article using product 33429, please notify us so that we can cite your literature.
et al,Targeting p63 upregulation abrogates resistance to MAPK inhibitors in melanoma.In Cancer Res on 2020 Apr 14. by Patel A, Fraile Garcia L, et al..PMID:32291316
, (2020),
PMID:
32291316
Yes
