Product Detail
Product NameJAK1 Antibody
Host SpeciesRabbit
ClonalityPolyclonal
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationsIHC IF
Species ReactivityHu Ms
SpecificityThe antibody detects endogenous levels of total JAK1 protein.
Immunogen TypePeptide
Immunogen DescSynthesized peptide derived from internal of human JAK1.
Target NameJAK1
ConjugateUnconjugated
Other NamesEC 2.7.10.2; JAK-1; JAK1; JAK1A; Janus kinase 1
Accession NoSwiss-Prot: P23458
NCBI Gene ID: 3716
Uniprot
P23458
Gene ID
3716;
Sdspage MW130kd
Concentration1.0mg/ml
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
StorageStore at -20˚C
Application Details
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JAK1 antibody #33721.
Immunofluorescence analysis of HeLa cells, using JAK1 antibody #33721.
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
Wilks A.F., Mol. Cell. Biol. 11:2057-2065(1991).
Lee S.-T., Oncogene 8:3403-3410(1993).
Lindholm C.K., Biochem. Biophys. Res. Commun. 296:929-936(2002).
If you have published an article using product 33721, please notify us so that we can cite your literature.
et al,Dietary quercetin potentiates the antiproliferative effect of interferon-α in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase
, (2017),
PMID:
29371942
Yes
