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Oct4 Antibody#35351

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Product Detail

Product NameOct4 Antibody

Host SpeciesRabbit

ClonalityPolyclonal

PurificationAntibodies were purified by antigen-affinity chromatography.

ApplicationsWB

Species ReactivityHu Ms

SpecificityThe antibody detects endogenous levels of total Oct4 protein.

Immunogen TypeRecombinant Protein

Immunogen DescRecombinant fragment corresponding to a region within amino acids 101 and 325 of OCT3/4.

Target NameOct4

ConjugateUnconjugated

Other NamesMGC22487 antibody; OTF-3 antibody; OTF3 antibody; OTF4 antibody; POU5F1 antibody; POU-type homeodomain-containing DNA-binding protein antibody; octamer-binding protein 3 antibody; POU domain transcription factor OCT4 antibody; octamer-binding protein 4 an

Accession NoSwiss-Prot#:Q01860;
NCBI Gene#:5460

Uniprot Q01860

Gene ID 5460;

Sdspage MW39kd

Concentration0.48mg/ml

FormulationRabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

StorageStore at -20˚C

Application Details

Western blotting: 1:500-1:3000

Sample (20 ug of whole cell lysate)
A: human ESC
10% SDS PAGE
#35351 diluted at 1:500
Sample (30 ug of whole cell lysate)

A: NIH-3T3

10% SDS PAGE

OCT3/4 antibody

#35351 diluted at 1:1000

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. [provided by RefSeq]

If you have published an article using product 35351, please notify us so that we can cite your literature.

et al,Exosomal TRIM3 is a novel marker and therapy target for gastric cancer.In J Exp Clin Cancer Res.On 2018 Jul 21 by Fu H, Yang H et al..PMID:30031392 , (2018),
PMID: 30031392
et al,H. pylori infection-induced MSC differentiation into CAFs promotes epithelial-mesenchymal transition in gastric epithelial cells.In Int J Mol Med on 2013 Dec by Zhang Q, Wang M,et al..PMID:24145921 , (2013),
PMID: 24145921
et al,Activation of mesenchymal stem cells by macrophages prompts human gastric cancer growth through NF-魏B pathway.In PLoS One on 2014 May 13 by Tingting Yang , Xu Zhang et al..PMID:24824968 , (2014),
PMID: 24824968
et al,Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness.In BMC Cancer on 2015 Oct 24 by Jianguo Xue , Yuan Zhu et al..PMID: 26498753 , (2015),
PMID: 26498753

NOTE

Application

  • WBWestern Blotting
  • IHCImmunohistochemistry
  • IFImmunofluorescence
  • ICCImmunocytochemistry
  • FCFlow Cytometry
  • IPImmunoprecipitation
  • EELISA
  • DBDot Blotting
  • ChIPChromatin Immunoprecipitation
  • GICAGold Immunochromatography Assay
  • NCNegative Control

Species Reactivity

  • HuHuman
  • MsMouse
  • RtRat
  • DmDrosophila melanogaster
  • CCaenorhabditis elegans
  • MkMonkey
  • RbRabbit
  • BBovine
  • DDog
  • PPig
  • HmHamster
  • ChHmChinese Hamster
  • ChkChicken
  • ShpSheep
;

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